BeNano 180 Zeta Pro - Nanoparticle Size and Zeta Potential Analyzer

The BeNano Series from Bettersize Instruments represents the current generation of nanoparticle size and zeta potential analyzers.

The system leverages the power of advanced dynamic light scattering (DLS), electrophoretic light scattering (ELS), and static light scattering (SLS) technologies to ensure the accurate measurement of particle size, zeta potential, and molecular weight.

The BeNano Series sees widespread use in academic and manufacturing processes across a range of application fields, including pharmaceuticals, chemical engineering, food and beverages, inks and pigments, life sciences, and many more areas.

Features and Benefits

  • A wide size range of 0.3 nm - 15 μm
  • A low minimum sample volume of 3 μL
  • Excellent sensitivity, thanks to the system’s APD (Avalanche Photodiode) detector
  • The option to automatically adjust laser intensity
  • Results can be evaluated via an intelligent algorithm
  • Advanced DLS backscattering (173 °) detection technology
  • User-adjustable scattering volume to accommodate concentrated samples
  • Powerful PALS (Phase Analysis Light Scattering) technology
  • A user-programmable temperature control system
  • Full compliance with 21 CFR Part 11, ISO 22412, and ISO 13099

Specifications

Source: Bettersize Instruments Ltd.

Functions Parameter BeNano 180 Zeta Pro BeNano 180 Zeta BeNano 90 Zeta BeNano
Zeta
BeNano
180 Pro
BeNano
180
BeNano
90
Size
measurement
Size
measurement range
0.3 nm - 15 μm* 0.3 nm - 10 μm* 0.3 nm - 15 μm* N/A 0.3 nm - 15 μm* 0.3 nm -10 μm* 0.3 nm - 15 μm*
Sample volume 3 μL - 1 mL* 40 μL - 1 mL* 3 μL - 1 mL* N/A 3 μL - 1 mL* 40 μL - 1 mL* 3 μL - 1 mL*
Detection angle 90° & 173° & 12° 173° & 12° 90° & 12° N/A 90° & 173° 173° 90°
Analysis algorithm Cumulants, General Mode, CONTIN, 
NNLS
Cumulants, General Mode, CONTIN, 
NNLS
Cumulants, General Mode, CONTIN, 
NNLS
N/A Cumulants, General Mode, CONTIN, 
NNLS
Cumulants, General Mode, CONTIN, 
NNLS
Cumulants, General Mode, CONTIN, 
NNLS
Upper limit of
concentration range
40% w/v* 40% w/v* Optically clear+ N/A 40% w/v* 40% w/v* Optically clear†
Detection position Movable position
0.4 - 5 mm
Movable position
0.4 - 5 mm
Fixed position
5 mm
N/A Movable position
0.4 - 5 mm
Movable position
0.4 - 5 mm
Fixed position
5 mm
Zeta potential
measurement
Detection angle 12° 12° 12° 12° N/A N/A N/A
Zeta potential
measurement range
No actual limitation No actual limitation No actual limitation No actual limitation N/A N/A N/A
Electrophoretic mobility  > ± 20 μm·cm/V·s > ± 20 μm·cm/V·s > ± 20 μm·cm/V·s > ± 20 μm·cm/V·s N/A N/A N/A
Conductivity 0 - 260 mS/cm 0 - 260 mS/cm 0 - 260 mS/cm 0 - 260 mS/cm N/A N/A N/A
Sample volume 0.75 - 1 mL 0.75 - 1 mL 0.75 - 1 mL 0.75 - 1 mL N/A N/A N/A
Sample size 2 nm - 110 μm 2 nm - 110 μm 2 nm - 110 μm 2 nm - 110 μm N/A N/A N/A
Other
measurements
Molecular weight
(Mw)
342 Da - 2 x 107 Da* 342 Da - 2 x 107 Da* 342 Da - 2 x 107 Da* N/A 342 Da - 2 x 107 Da* 342 Da - 2 x 107 Da* 342 Da - 2 x 107 Da*
Viscosity 0.01 cp - 100 cp* 0.01 cp - 100 cp* 0.01 cp - 100 cp* N/A 0.01 cp - 100 cp* 0.01 cp - 100 cp* 0.01 cp - 100 cp*
Interaction parameter
KD
No actual limitation No actual limitation No actual limitation N/A No actual limitation No actual limitation No actual limitation
Trend measurement Time and temperature Time and temperature Time and temperature Time and temperature Time and temperature Time and temperature Time and temperature
System
parameters
Temperature
control range
-15 ℃ - 110 ℃,
±0.1 ℃
-15 ℃ - 110 ℃,
±0.1 ℃
-15 ℃ - 110 ℃,
±0.1 ℃
-15 ℃ - 110 ℃,
±0.1 ℃
-15 ℃ - 110 ℃,
±0.1 ℃
-15 ℃ - 110 ℃,
±0.1 ℃
-15 ℃ - 110 ℃,
±0.1 ℃
Condensation control Dry air or nitrogen Dry air or nitrogen Dry air or nitrogen Dry air or nitrogen Dry air or nitrogen Dry air or nitrogen Dry air or nitrogen
Laser source 50 mW Solid-state laser, 671 nm#, Class 1 50 mW Solid-state laser, 671 nm#, Class 1 50 mW Solid-state laser, 671 nm#, Class 1 50 mW Solid-state laser, 671 nm#, Class 1 50 mW Solid-state laser, 671 nm#, Class 1 50 mW Solid-state laser, 671 nm#, Class 1 50 mW Solid-state laser, 671 nm#, Class 1
Correlator Up to 4000 channels,

1011 linear
dynamic range
Up to 4000 channels,

1011 linear
dynamic range
Up to 4000 channels,

1011 linear
dynamic range
Up to 4000 channels,

1011 linear
dynamic range
Up to 4000 channels,

1011 linear
dynamic range
Up to 4000 channels,

1011 linear
dynamic range
Up to 4000 channels,

1011 linear
dynamic range
Detector Avalanche photodiode
(APD)
Avalanche photodiode
(APD)
Avalanche photodiode
(APD)
Avalanche photodiode
(APD)
Avalanche photodiode
(APD)
Avalanche photodiode
(APD)
Avalanche photodiode
(APD)
Intensity control 0.0001% - 100%,
manual or automatic
0.0001% - 100%,
manual or automatic
0.0001% - 100%,
manual or automatic
0.0001% - 100%,
manual or automatic
0.0001% - 100%,
manual or automatic
0.0001% - 100%,
manual or automatic
0.0001% - 100%,
manual or automatic
Dimensions
(L x W x H)
62.5 x 40 x 24.5 cm
(22 kg)
62.5 x 40 x 24.5 cm
(22 kg)
62.5 x 40 x 24.5 cm
(22 kg)
62.5 x 40 x 24.5 cm
(22 kg)
62.5 x 40 x 24.5 cm
(22 kg)
62.5 x 40 x 24.5 cm
(22 kg)
62.5 x 40 x 24.5 cm
(22 kg)
Power supply AC 100-240 V,
50-60 Hz, 4A
AC 100-240 V,
50-60 Hz, 4A
AC 100-240 V,
50-60 Hz, 4A
AC 100-240 V,
50-60 Hz, 4A
AC 100-240 V,
50-60 Hz, 4A
AC 100-240 V,
50-60 Hz, 4A
AC 100-240 V,
50-60 Hz, 4A
Conformity
to standards
21 CFR Part 11, ISO 13321, ISO 22412, ISO 13099 21 CFR Part 11, ISO 13321, ISO 22412, ISO 13099 21 CFR Part 11, ISO 13321, ISO 22412, ISO 13099 21 CFR Part 11, ISO 13321, ISO 22412, ISO 13099 21 CFR Part 11, ISO 13321, ISO 22412, ISO 13099 21 CFR Part 11, ISO 13321, ISO 22412, ISO 13099 21 CFR Part 11, ISO 13321, ISO 22412, ISO 13099
Optional Accessories Disposable
micro-volume cuvette
40 - 50 μL 40 - 50 μL 40 - 50 μL N/A 40 - 50 μL 40 - 50 μL 40 - 50 μL
Micro-volume
glass cuvette
25 μL N/A 25 μL N/A 25 μL N/A 25 μL
Glass cuvette
with round opening
1 mL 1 mL 1 mL N/A 1 mL 1 mL 1 mL
Capillary sizing cell 3 - 5 μL N/A 3 - 5 μL N/A 3 - 5 μL N/A 3 - 5 μL
Dip cell kit 1 - 1.5 mL,
zeta potential measurement
for organic-based samples
1 - 1.5 mL,
zeta potential measurement
for organic-based samples
1 - 1.5 mL,
zeta potential measurement
for organic-based samples
1 - 1.5 mL,
zeta potential measurement
for organic-based samples
N/A N/A N/A

* Dependent on samples and accessories
† Up to 40% w/v using capillary sizing cell
# 10 mW 633 nm He-Ne laser available on request

Enhanced Size Resolution with DLS Flow Mode

Video Credit: Bettersize Instruments Ltd.

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