Posted in | Analytical Equipment | Particle Size Analyzers

BeNano 180 Zeta Pro - Nanoparticle Size and Zeta Potential Analyzer

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The BeNano Series from Bettersize Instruments represents the current generation of nanoparticle size and zeta potential analyzers.

The system leverages the power of advanced dynamic light scattering (DLS), electrophoretic light scattering (ELS), and static light scattering (SLS) technologies to ensure the accurate measurement of particle size, zeta potential, and molecular weight.

The BeNano Series sees widespread use in academic and manufacturing processes across a range of application fields, including pharmaceuticals, chemical engineering, food and beverages, inks and pigments, life sciences, and many more areas.

Features and Benefits

A wide size range of 0.3 nm - 15 μm
A low minimum sample volume of 3 μL
Excellent sensitivity, thanks to the system’s APD (Avalanche Photodiode) detector
The option to automatically adjust laser intensity
Results can be evaluated via an intelligent algorithm
Advanced DLS backscattering (173 °) detection technology
User-adjustable scattering volume to accommodate concentrated samples
Powerful PALS (Phase Analysis Light Scattering) technology
A user-programmable temperature control system
Full compliance with 21 CFR Part 11, ISO 22412, and ISO 13099

Specifications

Source: Bettersize Instruments Ltd.

Functions	Parameter	BeNano 180 Zeta Pro	BeNano 180 Zeta	BeNano 90 Zeta	BeNano Zeta	BeNano 180 Pro	BeNano 180	BeNano 90
Size measurement	Size measurement range	0.3 nm - 15 μm*	0.3 nm - 10 μm*	0.3 nm - 15 μm*	N/A	0.3 nm - 15 μm*	0.3 nm -10 μm*	0.3 nm - 15 μm*
	Sample volume	3 μL - 1 mL*	40 μL - 1 mL*	3 μL - 1 mL*	N/A	3 μL - 1 mL*	40 μL - 1 mL*	3 μL - 1 mL*
	Detection angle	90° & 173° & 12°	173° & 12°	90° & 12°	N/A	90° & 173°	173°	90°
	Analysis algorithm	Cumulants, General Mode, CONTIN, NNLS	Cumulants, General Mode, CONTIN, NNLS	Cumulants, General Mode, CONTIN, NNLS	N/A	Cumulants, General Mode, CONTIN, NNLS	Cumulants, General Mode, CONTIN, NNLS	Cumulants, General Mode, CONTIN, NNLS
	Upper limit of concentration range	40% w/v*	40% w/v*	Optically clear⁺	N/A	40% w/v*	40% w/v*	Optically clear†
	Detection position	Movable position 0.4 - 5 mm	Movable position 0.4 - 5 mm	Fixed position 5 mm	N/A	Movable position 0.4 - 5 mm	Movable position 0.4 - 5 mm	Fixed position 5 mm
Zeta potential measurement	Detection angle	12°	12°	12°	12°	N/A	N/A	N/A
	Zeta potential measurement range	No actual limitation	No actual limitation	No actual limitation	No actual limitation	N/A	N/A	N/A
	Electrophoretic mobility	> ± 20 μm·cm/V·s	> ± 20 μm·cm/V·s	> ± 20 μm·cm/V·s	> ± 20 μm·cm/V·s	N/A	N/A	N/A
	Conductivity	0 - 260 mS/cm	0 - 260 mS/cm	0 - 260 mS/cm	0 - 260 mS/cm	N/A	N/A	N/A
	Sample volume	0.75 - 1 mL	0.75 - 1 mL	0.75 - 1 mL	0.75 - 1 mL	N/A	N/A	N/A
	Sample size	2 nm - 110 μm	2 nm - 110 μm	2 nm - 110 μm	2 nm - 110 μm	N/A	N/A	N/A
Other measurements	Molecular weight (Mw)	342 Da - 2 x 10⁷ Da*	342 Da - 2 x 10⁷ Da*	342 Da - 2 x 10⁷ Da*	N/A	342 Da - 2 x 10⁷ Da*	342 Da - 2 x 10⁷ Da*	342 Da - 2 x 10⁷ Da*
	Viscosity	0.01 cp - 100 cp*	0.01 cp - 100 cp*	0.01 cp - 100 cp*	N/A	0.01 cp - 100 cp*	0.01 cp - 100 cp*	0.01 cp - 100 cp*
	Interaction parameter K_D	No actual limitation	No actual limitation	No actual limitation	N/A	No actual limitation	No actual limitation	No actual limitation
	Trend measurement	Time and temperature	Time and temperature	Time and temperature	Time and temperature	Time and temperature	Time and temperature	Time and temperature
System parameters	Temperature control range	-15 ℃ - 110 ℃, ±0.1 ℃	-15 ℃ - 110 ℃, ±0.1 ℃	-15 ℃ - 110 ℃, ±0.1 ℃	-15 ℃ - 110 ℃, ±0.1 ℃	-15 ℃ - 110 ℃, ±0.1 ℃	-15 ℃ - 110 ℃, ±0.1 ℃	-15 ℃ - 110 ℃, ±0.1 ℃
	Condensation control	Dry air or nitrogen	Dry air or nitrogen	Dry air or nitrogen	Dry air or nitrogen	Dry air or nitrogen	Dry air or nitrogen	Dry air or nitrogen
	Laser source	50 mW Solid-state laser, 671 nm^#, Class 1	50 mW Solid-state laser, 671 nm^#, Class 1	50 mW Solid-state laser, 671 nm^#, Class 1	50 mW Solid-state laser, 671 nm^#, Class 1	50 mW Solid-state laser, 671 nm^#, Class 1	50 mW Solid-state laser, 671 nm^#, Class 1	50 mW Solid-state laser, 671 nm^#, Class 1
	Correlator	Up to 4000 channels, 10¹¹ linear dynamic range	Up to 4000 channels, 10¹¹ linear dynamic range	Up to 4000 channels, 10¹¹ linear dynamic range	Up to 4000 channels, 10¹¹ linear dynamic range	Up to 4000 channels, 10¹¹ linear dynamic range	Up to 4000 channels, 10¹¹ linear dynamic range	Up to 4000 channels, 10¹¹ linear dynamic range
	Detector	Avalanche photodiode (APD)	Avalanche photodiode (APD)	Avalanche photodiode (APD)	Avalanche photodiode (APD)	Avalanche photodiode (APD)	Avalanche photodiode (APD)	Avalanche photodiode (APD)
	Intensity control	0.0001% - 100%, manual or automatic	0.0001% - 100%, manual or automatic	0.0001% - 100%, manual or automatic	0.0001% - 100%, manual or automatic	0.0001% - 100%, manual or automatic	0.0001% - 100%, manual or automatic	0.0001% - 100%, manual or automatic
	Dimensions (L x W x H)	62.5 x 40 x 24.5 cm (22 kg)	62.5 x 40 x 24.5 cm (22 kg)	62.5 x 40 x 24.5 cm (22 kg)	62.5 x 40 x 24.5 cm (22 kg)	62.5 x 40 x 24.5 cm (22 kg)	62.5 x 40 x 24.5 cm (22 kg)	62.5 x 40 x 24.5 cm (22 kg)
	Power supply	AC 100-240 V, 50-60 Hz, 4A	AC 100-240 V, 50-60 Hz, 4A	AC 100-240 V, 50-60 Hz, 4A	AC 100-240 V, 50-60 Hz, 4A	AC 100-240 V, 50-60 Hz, 4A	AC 100-240 V, 50-60 Hz, 4A	AC 100-240 V, 50-60 Hz, 4A
	Conformity to standards	21 CFR Part 11, ISO 13321, ISO 22412, ISO 13099	21 CFR Part 11, ISO 13321, ISO 22412, ISO 13099	21 CFR Part 11, ISO 13321, ISO 22412, ISO 13099	21 CFR Part 11, ISO 13321, ISO 22412, ISO 13099	21 CFR Part 11, ISO 13321, ISO 22412, ISO 13099	21 CFR Part 11, ISO 13321, ISO 22412, ISO 13099	21 CFR Part 11, ISO 13321, ISO 22412, ISO 13099
Optional Accessories	Disposable micro-volume cuvette	40 - 50 μL	40 - 50 μL	40 - 50 μL	N/A	40 - 50 μL	40 - 50 μL	40 - 50 μL
	Micro-volume glass cuvette	25 μL	N/A	25 μL	N/A	25 μL	N/A	25 μL
	Glass cuvette with round opening	1 mL	1 mL	1 mL	N/A	1 mL	1 mL	1 mL
	Capillary sizing cell	3 - 5 μL	N/A	3 - 5 μL	N/A	3 - 5 μL	N/A	3 - 5 μL
	Dip cell kit	1 - 1.5 mL, zeta potential measurement for organic-based samples	1 - 1.5 mL, zeta potential measurement for organic-based samples	1 - 1.5 mL, zeta potential measurement for organic-based samples	1 - 1.5 mL, zeta potential measurement for organic-based samples	N/A	N/A	N/A